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Mitochondrial Biology Lab

Dept of Biochemistry, Indian Institute of Science, Bangalore.

Gautam Susarla

Integrated PhD Student

IISc Fellowship

B.Sc Life Sciences, Osmania University, Hyderabad, Telangana

Research Summary

My work involves the analysis of yeast DJ-1 homologs which are multifunctional and provides stress tolerance, however they are under studied and its investigation would unravel key features of human DJ-1. Reactive carbonyls such as methylglyoxal and glyoxal generated during various metabolism have deleterious effects on vital components of cell. Therefore, my project comprises detailed study of Saccharomyces cerevisiae Hsp31 proteins in regulating carbonyl toxicity.


Double DJ-1 domain containing Arabidopsis DJ-1D is a robust macromolecule deglycase

Melvin Prasad*, Priyanka Kataria*, Sunayana Ningaraju, Radhika Buddidathi, Kondalarao Bankapalli, Swetha Chenna, Gautam Susarla, Radhika Venkatesan, Patrick D’Silva#, P. V. Shivaprasad#

New Phytologist, 2022 Jul

Redox-dependent Regulation of Mitochondrial Dynamics by DJ-1 Paralogs in Saccharomyces Cerevisiae

Kondalarao Bankapalli, Vinaya Vishwanathan, Gautam Susarla, Ningaraju Sunayana, SreeDivya Saladi, Divya Peethambaram, Patrick D'Silva

Redox Biology, 2020 Feb