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Mitochondrial Biology Lab

Dept of Biochemistry, Indian Institute of Science, Bangalore.

Principal Investigator

Patrick D' Silva

Prof. Patrick D' Silva
Professor

Post Doctoral Fellows

parth

Dr. Parthsarathi Nayak

Post Doctoral Fellowship

PhD Students

abhijit

Abhijit Birje

PhD Student

vinaya

Vinaya Vishwanathan

PhD Student

Abhishek

Abhishek Kumar

PhD Student

ena

Ena Dhaddha

PhD Student

tejashree

Tejashree Waingankar

PhD Student

sanjay

Sanjay Prasad

PhD Student

gautamsusarla

Gautam Susarla

Integrated PhD Student

priyanka

Priyanka Kataria

Integrated PhD Student

anjali

Anjali

Integrated PhD Student

sanandha

Sanandha

PhD Student

Research Fellows

vigneshwaran

Vigneshwaran R

Senior Research Fellow

saravana

Saravana Raja R

Project Assistant

Alumnus Students

Name

PhD

Position

Locality

------- ------ ------------ ------------

Abhishek Kumar

2020 Submitted Thesis -------

Dr. Srujan Kumar Matta

2020 Post Doctoral Researcher UT Southwestern Medical Center, Dallas, Texas, USA

Dr. Namrata Singh

2019 Research Associate Imperial College London, UK

Dr. Kondalarao B

2018 Post Doctoral Fellow University of Washington, Seattle, USA

Dr. Shubhi Srivastava

2017 Post Doctoral Fellow University of Illinois, Illinois, USA

Dr. Prasenjit Prasad Saha

2015 Post Doctoral Fellow Dr. Stanely L Hazen's Lab, Cleveland Clinic, Cleveland, OH

Dr. Madhuja Samaddar

2015 Postdoctoral Researcher Cynthia Kenyon's Lab, Calico Labs, South San Francisco, CA

Dr. Gautam Pareek

2014 Post Doctoral Fellow Prof. Dan Gottschling Lab, FHCRC, Seattle, USA.

Dr. Devanjan Sinha

2014 Assistant Professor Institute of Science, Banaras Hindu University, Uttar Pradesh, India.

Dr. Arvind Vittal Goswami

2014 Post Doctoral Fellow Prof. Gerald S Shadel Lab, Yale University, USA.

Dr. Anushikha Thakur

2012 Assistant Scientific Manager Biocon, Bangalore, India.

Alumnus Project Assistants & Post Doctoral Fellow

Name

Position

Locality

------- ------------ ------------

Saladi Sreedivya

PhD Student Kaiserslautern University of Technology, Kaiserslautern, Germany

Dr. Anjaneya Oblesha

Assistant Professor Sri Lakshmi Venkatesh Desai College, Raichur

Arunraj S.P

PhD Student Max Planck Institute for Evolutionary Biology, Plon, Germany

Dr. Praveen Kumar.S.K

Asst. Professor Karnatak University, Dharwad, Karnataka

Pushpa Hegde

PhD Student INSERM, Centre de Recherche des Cordeliers, Paris, France

Ambika Nadkarni

PhD Student University of Illinois, Urbana-Champaign, USA.

Vinoth Babu Veedin Rajan

PhD Student Max F.Perutz Laboratories,Vienna Biocenter GmbH.

Balasubramanyam C

PhD Student Umea university, Sweden.

Akhil Sarogi

M.Tech Student IIT, Kharagpur

Saroj Yadav

PhD Student Monash Research academy, IIT, Mumbai.

Shanthi

SRF-ICMR Periyar University,Salem.

Nagarajan N.S

Associate Developer Coextrix Technologies,Bangalore.

Ratheesh Kumar.R

API Developer-Php Sixth Energy Technologies pvt.ltd, Bangalore.

Sahezeel Awadia

PhD Student University of Toledo, Ohio, USA.

Ajeet Singh

PhD Student IIT, Kharagpur, India

Vivekanandhan Krishnamoorthy

Research Associate DuPont India, Hyderabad, India.

Dr. Priyanka Samji

Associate Professor MLACW, Bangalore, India.

Devipriya Rajkumar

PhD Student Institute of Toxicology and Genetics, Lucknow, India

Neha Joshi

- -

Lekshmi Krishna

- -

Prashanna Kumar R.S

- -

Purushotham Jaya

Transgenic Assistant National Mouse Transgenic Facility, NCBS, Bangalore.

Vinoth Kumar E

Web Developer TROPPUS Web Services, Bangalore, India

Lakshmi Prasanna

- Marseille, France

Abhijit Birje

PhD Student
abhijit

Credentials


Present Status: PhD in Biological Sciences, IISc, Bangalore.

Fellowships

IISc PhD Fellowship.

Summary of Research


yet to update....

Hobbies



Photography

Parthsarathi Nayak

Post Doctoral Fellow
partha

Credentials

B.Sc. in Biotechnology, Utkal Universty
M.Sc. in Biotechnology, Sambalpur University
Ph.D. in LifeScience, National Institute of Technology Rourkela, India.
Research Associate in School of Biotechnology, JNU, India
Present Status: Research Associate in Biochemistry, IISc Bangalore, India

Fellowships

DBT RA

Summary of Research




Nanozymes are the nanomaterials which mimic the enzyme characteristics. These are the trending materials with very high stability and efficiency in catalyzing important metabolic processes in-vitro and in-vivo. Compared to natural enzymes, Nanozymes are less expensive, easy to manufacture and can be stored for longer time. Despite the potential application of bare nanoparticles, we hypothesize that improved surface functionalization of nanoparticles with active entities could enhance specific targeting and cellular uptake with tuneable coronas.
As per my experience, I would like to implement my nanoparticles functionalization expertise to oxidative stress related disorder.
“The idea is to use therapeutic NPs with functionalized corona to rescue the cells from oxidative stress by mimicking the function of major antioxidant enzymes i.e. catalase, glutathione peroxidase and superoxide dismutase thereby preventing ROS-mediated neurological disorder”


Hobbies


Badminton, Watching Movies and Travelling

Vinaya Vishwanathan

PhD Student
vinaya

Credentials


Present Status: PhD in Biological Sciences, IISc, Bangalore.

Fellowships

IISc PhD Fellowship.

Summary of Research


yet to update....

Hobbies



Abhishek Kumar

PhD Student
abhishek

Credentials


B.Sc. Honours in Biotechnology, Science College, Patna.
M.Sc. in Genomics, Madurai Kamaraj University, Madurai.
Present Status: PhD in Biological Sciences, IISc, Bangalore.

Fellowships

CSIR-JRF.

Summary of Research


Mitochondria are dynamic eukaryotic organelles critical for cellular viability due to their pivotal role in energy production, biosynthetic pathways, and signaling activities. Proper mitochondrial functioning relies on accurate and efficient trafficking of numerous proteins from the cytosol to their precise location into the organelle. Sophisticated protein machinery commonly referred to as translocases, present at the outer and inner mitochondrial membranes, mediate this process. Although decades of research have identified different translocase complexes across the mitochondrial membrane, the exact mechanism of protein import through different translocons is not clearly understood.

I am interested in understanding how protein trafficking occurs across the inner mitochondrial membrane. The inner membrane contains two distinct translocon machinery: carrier translocase (TIM22 complex) and presequence translocase (TIM23 complex). The TIM22 complex facilitates the integration of complex polytopic inner membrane proteins. My work focuses on deciphering the architecture of the TIM22 complex and its plausible role in modulating the organelle's biogenesis and quality control using yeast as a model system.

Hobbies


Playing Cricket, Table Tennis and other sports
Bike Ridding

Ena Dhaddha

PhD Student
ena

Credentials


Present Status: PhD in Biological Sciences, IISc, Bangalore.

Fellowships

yet to update

Summary of Research


yet to update....

Hobbies



Tejashree Waingankar

PhD Student
tejashree

Credentials

M.Sc in Biotechnology, Savitribai Phule Pune University, Pune.
Present Status: Ph.D in Biological Sciences, IISc-Bangalore.

Fellowships

Research fellowship CSIR-JRF

Summary of Research



Yet to update



Sanjay Prasad

PhD Student
sanjay

Credentials

B.Pharma.: Muzaffarpur Institute of Technology, Bihar University, Muzaffarpur
M.Tech in Biotechnology, Anna University, Chennai
Present Status: Senior Scientific Officer, Dept. of IPC, IISc, Bangalore

Fellowships


Yet to update!

Summary of Research


yet to update....

Hobbies



Badminton

Gautam Susarla

Integrated PhD Student
gautamsusarla

Credentials

B.Sc Life Sciences, Osmania University, Hyderabad, Telangana
Present Status: Integrated PhD in Biological Sciences, IISc,Bangalore

Fellowships



Summary of Research


My work involves the analysis of yeast DJ-1 homologs which are multifunctional and provides stress tolerance, however they are under studied and its investigation would unravel key features of human DJ-1. Reactive carbonyls such as methylglyoxal and glyoxal generated during various metabolism have deleterious effects on vital components of cell. Therefore, my project comprises detailed study of Saccharomyces cerevisiae Hsp31 proteins in regulating carbonyl toxicity.

Hobbies


Playing Football
Bike Riding
Swimming
Wildlife Trekking

Priyanka Kataria

Integrated PhD Student
priyanka

Credentials


B.Sc. Botany Hons. Daulat Ram College, University of Delhi

Fellowships


IISc Fellowship

Summary of Research


Plants being sessile organisms are constantly exposed to different abiotic and biotic stresses, hence they have evolved various strategies to overcome these deleterious conditions. DJ-1 superfamily proteins are found across various species, they have been identified as multi-stress responding proteins. However, role of DJ-1 family proteins in plants is still elusive. My research project is to understand the structural and functional role of DJ-1 paralogs of Arabidopsis thaliana.

Hobbies


Swimming

Anjali

Integrated PhD Student
anjali

Credentials


BSc (hons) in zoology, Hansraj College, Delhi University.

Fellowships


IISc Fellowship

Summary of Research


yet to update....

Hobbies


Hobbies- writing, singing, poetry, badminton.

Sananda Biswas

PhD Student
sananda

Credentials


Yet to update!

Fellowships



Summary of Research


yet to update....

Hobbies



Vigneshwaran Renganathan

Senior Research Fellow
name

Credentials


B.Sc in Biochemistry from Bharathidasan University, Trichy
M.Sc in Bioinformatics from Bharathidasan University, Trichy

Saravana Raja

Junior Research Fellow
name

Credentials


M.Tech in Bioinformatics from Bharathidasan University, Trichy