Welcome to HSPIR Database
HSPIR is a manually curated online database which provides comprehensive information on six major Heat Shock Proteins(HSPs) viz., sHsp (HSP20), Hsp40 (J-Proteins), Hsp70 (DnaK/Ssa), Hsp60 (Chaperonin), Hsp90 (HtpG) and Hsp100 (Clp). HSPs are highly conserved and ubiquitous group of proteins present in all living organisms. HSPs play a critical role in maintaining protein homeostasis by re-establishing functional native conformation of proteins during unfavourable conditions such as elevated temperatures and other stresses. HSPs inludes a vast repertoire of functions such as de novo protein folding, disaggregation and protein trafficking. This makes HSPs a valuable resource for researchers studying the protein folding and resistance and survival of pathogens. HSPs and their classification are further described here. To know more about individual HSP family, click on the particular HSP system from the figure below.
HSPIR currently harbors 9902 protein records encompassing 277 completed genomes covering prokayotic and eukaryotic species. The current complete statistics of HSPIR is mentioned in the table below.